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中文
CRISPR/Cas9基因编辑通过gRNA和供体寡核苷酸，产生了一个C到T的突变（c.274C>T），将arginine的密码子92替换为tryptophan的密码子（p.R92W）。这个突变模拟了46,XX性发育性别分化异常（DSD）患者中发现的特定变异（来源：J:277036）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
