在第五个外显子位置插入了LoxP引导的neo选择元件, Western blot结果显示纯合突变小鼠中没有蛋白表达(来源:J:265916)
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A loxP flanked neo selection cassette was inserted into the 5th exon. Western blot analysis confirmed the absence of protein expression in homozygous mutant mice. (J:265916)