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中文
7.2kb的Tg4-42转基因是通过Thy1启动子驱动，将人类Abeta 4-42连接到小鼠促甲状腺素释放激素信号肽，设计成表达的。转基因小鼠表达的是去N端的Abeta 4-42(4-42位氨基酸)，这是一种在阿尔茨海默病(AD)患者大脑中能促进Abeta聚集的肽。创始系2是转基因表达量最高的，其体内含有超过20个拷贝，且最后一个拷贝是反向排列的。(来源：J:275188)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
