带有Gt(ROSA)26Sortm1(rtTA2S-M2)Jae突变的ES细胞被重定向了。这些细胞被注射了一种"翻转质粒", 包含tetacycline响应元件(TRE或tetO)以及带有HA标签的 mouse Nup88基因序列,以及一个带有Flpe重组酶的质粒,以便于将tetO-Oct4整合到Col1a1基因的3' UTR区域。(来源:J:231166)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
24
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部