通过CRISPR/Cas9基因编辑技术产生了一个11bp的缺失突变。 Western blot结果显示,成年纯合雄性小鼠的睾丸中没有检测到蛋白质表达(来源:J:254851)
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An 11 bp deletion was generated by CRISPR/Cas9 mutagenesis. Western blot analysis confirmed the absence of protein expression in the testes of adult homozygous male mice. (J:254851)