在这个微小RNA簇中,Mir23a、Mir27a、Mir3074-2和Mir24-2通过同源重组被一个由EM7/PGK启动子驱动的puromycin/thymidine kinase融合基因替换,该基因由LoxP和F3/FRT序列 flank。选择子通过Cre介导的重组被剔除。(来源:J:258947)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
基因间区删除
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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