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中文
基于Mouse BAC RP23-318M13构建了导向载体。在包含HS1-HS5(HS5-1)敏感性区域序列的下游位置插入了loxP位点。上游插入了由loxP位点引导的诺卡因抗性基因座，随后通过体外Cre介导的重组去除，留下一个位于区域上游的loxP位点。接着，在5'的loxP位点上游插入了由FRT位点引导的诺卡因基因座，通过后续的Flp介导重组将其去除。调节区域位于Pcdha基因簇下游，调控其基因的表达(来源：J:277249)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
