这个IMPC的等位基因是在瑞士罗氏研究所通过向小鼠猴模型注射Cas9 RNA和四个指导序列(CAGCTGATAGGGCGTGCCATGGG, CCCCGAGACTTTCCATTGTTTGG, TCCATCCCCCAGGCTTTCATGGG, AGCTTAGCAATCTAGATGATGGG)产生的,导致了外显子的缺失。(来源:J:237616)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count