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中文
在编码区域，通过微注射Cas9 mRNA、Scr7、两个sgRNAs和一个包含目标的GC>AG替换以及三个silent替换的ssODN(单链脱氧核糖核酸)来创建了p.Arg229Gln突变。这种R229Q变异在一些重症联合免疫缺陷症(SCID)和奥门恩综合症(OS)患者中被发现。(来源：J:276940)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
