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中文
L1L2_Bact_P cassette被插入到染色体4的120,319,789位点，位于关键外显子（构建GRCm39）。该 cassette包含FRT位点、lacZ序列和一个loxP位点。FRT位点后面跟着由人类β-actin启动子驱动的诺卡因抗性基因、SV40polyA，然后是一个第二个FRT位点和第二个loxP位点。插入该cassette造就了一只报告基因敲除小鼠。通过Cre介导的亲本等位基因剔除导致了驱动诺卡因选择性筛选的promoter元件去除，留下插入的lacZ报告序列。欲了解针对此IKMC等位基因以及其他类似策略的详细信息，请访问http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml(来源：J:157065)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
