这个转基因构建包含了一个经过修改的完整人类cDNA,它被插入在CAG启动子/增强子和兔子β-球蛋白的poly(A)信号序列之间。为了促进编码肽的分泌,cDNA通过替换了人类信号肽序列,采用的是鸡的同源序列进行了改造。(来源:J:276687)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL x BALB/c
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插入
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1
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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