这个来自TCPR0740项目的等位基因是在基因组表型学中心通过向细胞注射Cas9核酸酶和三组引导RNA,它们带有AGTGGACCCATGCAATGCTT和CAAACAAGCTTCTCCCTATC的特定 Spacer 序列,目标是ENSMUSE00000452230基因的5'端和3'端。这导致了chr15染色体上一个838bp的缺失,起始位置在43,866,756,结束于43,867,593(GRCm38建库参考)。(J:200814)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
基因内删除
--
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部