这个来自TCPR0749项目的等位基因是在表型遗传学中心通过向细胞中注入Cas9的核糖核酸同质体,结合两个单链向导RNA,带有spacer序列TGCCTCAGCAAGATTTAAAC和GGTTCAAGCTATGGATTCTG,同时伴随一个包含loxP位点的长单链DNA模板,这些位点位于Cas9切割的外显子ENSMUSE00000269846两侧产生的(来源:J:200814)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
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1
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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