Log In|Sign Up
中文
含有第143位氨基酸由 glutamate 改为 lysine 的人类心肌肌动蛋白轻链（E143K）由心脏特异性的α-MHC启动子控制。这种突变与人类的限制性心肌病有关。Line 2 表达的约相当于55%的人类心肌轻链，替代了内源性小鼠心肌轻链。（来源：J:258831）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
