将一个人类的MYC基因,前有带有三倍polyadenylation序列的neo cassette删除元件,后接有IRES-EGFP的启动子,插入到ROSA定位序列中。这种融合蛋白的表达只有通过Cre介导的neo cassette及其polyadenylation序列的去除才能实现。(来源:J:263858)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
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--
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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