将一个人类的MYC基因,前有带有三倍polyadenylation序列的neo cassette删除元件,后接有IRES-EGFP的启动子,插入到ROSA定位序列中。这种融合蛋白的表达只有通过Cre介导的neo cassette及其polyadenylation序列的去除才能实现。(来源:J:263858)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count