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中文
Exon 2被修改，通过替换第23位的天冬氨酸为异亮氨酸(Asp23Ala)，以及第24位的赖氨酸为甘氨酸(K24G)，目的是阻断胰蛋白酶原的激活。随后，通过Cre介导的重组移除了含有的 Neo抗性筛选标记。(来源：J:267764)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
