在exon 11的上游插入了一个带有5' loxP位点的FRT引导的诺姆霉素抗性基因座,随后在exon 12的下游插入了另一个loxP位点。通过Flp介导的重组,去除了选择性基因座,使得exons 11和12成为可删除的(来源:J:274977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
1
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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