在9号染色体的v38版本,由ENU诱导的A到T的转换发生在45,001,128号碱基对(基因为chr9:45,001,128),或者在NC_000075的GenBank基因组区域的8,537号位置,该区域编码Cd3e。这个变异等同于mRNA序列NM_007648中第416位的氨基酸,位于共有8个外显子的第6个外显子内。该变异导致CD3蛋白中第106位的谷氨酸被缬氨酸取代,即E106V。(参考文献:J:274934)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
隐性
1
2
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部