在7号染色体的v38位置,由ENU诱导的T到C的转换发生在122,289,514号碱基对,或者在GenBank的NC_000073基因组区域的第390位。这个变异对应于NM_008855 mRNA序列中第17个总exons的第390位氨基酸,导致了异亮氨酸(ILE)变为苏氨酸(I57T)的替换。(参考文献:J:274860)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
半显性
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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