Log In|Sign Up
中文
这项研究通过CRISPR/Cas9技术对基因进行了靶向。使用了四条sgRNA，两条针对基因编码区域上游，两条针对下游，再加上Cas9 mRNA，注射到了(B6 x D2)F1的卵母细胞的核中。十个候选小鼠品系中，选用了线5进行后续实验。这些小鼠的等位基因在基因上有一个912bp的缺失。（来源：J:274740）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
