Lcn3^em3Btlr

The CRISPR/Cas9 system and sgRNA 5'-AGACGACATCCCAATAAACA-3' was used to generate the mice. The CRISPR/Cas9 system generated a 2-base pair deletion CA at c.391_392del (NM_010694.2). The mutation is predicted to cause a frame-shifted protein product beginning after amino acid 117 of the protein and termination after the inclusion of three aberrant amino acids. (J:274568)