Lmbr1l^em1Btlr

The CRISPR/Cas9 system and sgRNA 5'-TGCACTCGCGGACCCTGTCG-3' was used to generate the mice. The CRISPR/Cas9 system generated a 2-base pair deletion at c.231_232del (NM_029098.3). The mutation is predicted to cause a frame-shifted protein product beginning after amino acid 17 of the protein and premature termination after the inclusion of 30 aberrant amino acids. (J:274568)