Rasgrp1^m5Btlr

ENU-induced A to G transition at base pair 117,282,654 (v38) on chromosome 2, or base pair 60,224 in the GenBank genomic region NC_000068 encoding Rasgrp1. The mutation corresponds to residue 2,444 in the mRNA sequence NM_011246 within exon 17 of 17 total exons. The mutation results in an aspartic acid to glycine substitution at position 759 (D759G) in the RasGRP1 protein. (J:272846)