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中文
CRISPR/Cas9基因编辑技术用于在exon 2的TCA野生型苏氨酸密码子替换为TTA亮氨酸密码子(S55L)。小鼠的S55L突变等同于人类的S59L突变。人类CHCHD10基因的变异可导致前额叶-颞叶痴呆和肌萎缩侧索硬化症（ALS，来源：J:272524）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
