Prkdc^M15Btlr

ENU-induced T to C transition at base pair 15,752,764 (v38) on chromosome 16, or base pair 115,322 in the GenBank genomic region NC_000082 for Prkdc. The mutation corresponds to residue 6,933 in the mRNA sequence NM_011159 within exon 52 of 86 total exons. The mutation results in a serine to proline substitution at position 2,304 (S2304P) in the DNA-PKCS protein. (J:272445)