Ptpn6^m6Btlr

ENU-induced A to G transition at base pair 124,724,984 (v38) on chromosome 6, or base pair 13,726 in the GenBank genomic region NC_000072. The mutation corresponds to residue 1,535 in the mRNA sequence NM_013545 within exon 11 of 16 total exons. The mutation results in a histidine to arginine substitution at position 445 (H445R) in variant 1 of the SHP1 protein. (J:272439)