这个靶向载体从5'到3'包含了内部核糖体进入序列(IRES,允许mRNA序列中部的翻译起始),Cre重组酶序列,牛生长激素的polyA序列,以及一个Frt标记的PGK-Neo-bGHpA插入片段。杂交小鼠与FLPe小鼠杂交,以实现PGK-Neo-bGHpA片段的遗传剔除。(来源:J:269094)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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