Jak3^M5Btlr

ENU-induced A to G transition at base pair 71,685,404 (v38) on chromosome 8, or base pair 9,022 in the GenBank genomic region NC_000074 encoding Jak3. The mutation corresponds to residue 2,708 in the mRNA sequence NM_010589 within exon 19 of 25 total exons. The mutation results in a glutamic acid to glycine substitution at position 833 (E833G) in the JAK3 protein. (J:272399)