在exon 2的上游插入了一个loxP位点。在exon 4的上游插入了一个带有3' loxP的FRT引导的诺卡因抗性元件,同样也包含一个loxP位点。通过Flp介导的重组移除了FRT引导的诺卡因元件。随后,Cre介导的重组去除了exons 2和3。(来源:J:237978)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
基因内删除
--
1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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