在7号染色体的v38版本,由ENU诱导的A到G的转换发生在43,409,057号碱基对(基因为7号染色体),或者在GenBank的NC_000073基因组区域的第865位。这个变异对应于mRNA序列NM_172900中第123位的氨基酸,位于第3个外显子。该突变导致Siglec-G蛋白中赖氨酸(arginine, R)被替换为甘氨酸(glycine, G),位置为R123G。(引用:J:272021)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
半显性
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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