这个IMPC的等位基因是在威康信托桑格研究所通过注入Cas9 RNA和四个引导序列(CCTGGTGTTGATTTTAGGCCCAA, CCGGATGTGGCACAACCAGAGTT, CCCACAACTATAAATCCACAGTG, GCAGGCAGGAACATATATCTTGG)产生的,导致了Exon的缺失。(来源:J:265051)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count