叙利亚仓鼠朊蛋白的启动子驱动了猪囊尾蚴朊蛋白的开放阅读框cDNA在大脑中的表达(使用cos.Tet质粒构建了转染基因)。生成了三条品系,23441、23447和23454。这些品系中表达的蛋白质大约是野生型小鼠的2.5倍,并且据估算,其表达水平大约是猪的3倍。(来源:J:236012)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB.129S7(B6)-Prnptm1Cwe/J
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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