在exon 7的上游插入了一个floxed neomycin筛选 cassette,然后在exon 7的下游放置了STOP cassette、一个loxP位点和一个YFP报告基因。通过Cre介导的重组,去除了floxed neo cassette(来源:J:85808)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count