通过loxP位点的Cre介导重组,10-12外显子被删除了。小肠来源的蛋白质经 Western blot 分析后,未检测到该等位基因的可检测蛋白表达。(来源:J:229247)
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Exons 10-12 were deleted by cre-mediated recombination of flanking loxP sites. Western blot analysis of proteins from small intestine showed that no detectable protein product was expressed from this allele. (J:229247)