CRISPR通过5'gRNA(5'-TGCCATCCGATGCAATGCGCAGG-3')定位在exon 2的上游和3'gRNA(5'-AGGCAAGTTGGGCGTACTGCTGG-3')定在exon 5的下游,设计用于消除9938bp的变异。(来源:J:287088)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count