Abca2^em1(IMPC)J

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TCCCCTTCCAACAGAGACCG and TCTAACCCTAAAGCTCCCCT, which resulted in a 2972 bp deletion beginning at Chromosome 2 position 25,432,845 bp and ending after 25,435,816 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000240810-ENSMUSE00000240762 (exons 3 through 9) and 1710 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 53 and early truncation 2 amino acids later. (J:188991)