在13号染色体的enu诱导的T到A替换,位置在979,338,410号碱基(基因v38),或者在NC_000079的GenBank基因组区域的148,382号碱基,这个变异对应于NM_001111324 mRNA序列中第3个外显子的410号氨基酸位置。这个突变导致NEDD9蛋白中 cysteine 18 被替换为一个早终止密码子(C18*)。(参考文献:J:267702)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
隐性
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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