Wdr74^em1(IMPC)J

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGAAACGGCTTGGGCTTCCA and GATAGAGTAGGTAGGTTGCA, which resulted in a 992 bp deletion beginning at Chromosome 19 position 8,737,406 bp and ending after 8,738,397 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000235265-ENSMUSE00000235241 (exons 4-6) and 667 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 98 and early truncation 14 amino acids later. (J:188991)