这个IMPC的等位基因是由巴约医学院通过向细胞注射Cas9 RNA和三个引导序列(CCCCTTCGCGCGGCGGGAAGGCG, GAGAACCCGTGGGCGGCGAAGGG, GTGGAATTGTGGCGCGTTGGCGG)产生的,导致了Exon的缺失。(来源:J:265051)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count