Sall4基因的exon1被替换成了GFP-Cre-ERT2的启动子-Cre-ERT2融合基因,随后通过同源重组插入了Frt flank的neo标记。产生的小鼠与Flpo小鼠杂交,以剔除neo标记。(来源:J:266804)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入,基因内删除
--
1
5
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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