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中文
七重复的四环素操作子序列驱动人类EGFR(带有T790M突变和第19外显子缺失，del E746_A750)的诱导性表达。通过在特定组织特异性启动子驱动下，表达tetracycline激活子(tTA)或反激活子(rtTA)的这些转基因小鼠，可以通过给予/停用多西环素来诱导在感兴趣的组织或细胞类型中表达这种突变基因。(来源：J:156440)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
