CRISPR技术删除了3' UTR中第6外显子内一个包含两个Hex(AAUAAA)和2个Cytoplasmic Polyadenylation Elements(细胞质poly(A)位点)的377bp区域。这个区域存在于长转录本中。生成了线30(UCp1em1Yshu)和线64(UCp1em2Yshu)。(引用:J:266624)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count