CRISPR技术删除了3' UTR中第6外显子内一个包含两个Hex(AAUAAA)和2个Cytoplasmic Polyadenylation Elements(细胞质poly(A)位点)的377bp区域。这个区域存在于长转录本中。生成了线30(UCp1em1Yshu)和线64(UCp1em2Yshu)。(引用:J:266624)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Endonuclease-mediated
基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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