Rsph6a^em2Osb

CRISPR/cas9 mediated recombination created a 12,068 bp deletion spanning from exon 1 to exon 4. This deletion removes amino acids 122-542 of the long isoform (variant 1) and amino acids 122-289 of the short isoform (variant 2). Western blot analysis confirmed the absence of expression in homozygous mice. (J:266136)