受精卵的核中注入了含有7.6千碱基的从小鼠乳清酸蛋白基因上游序列的质粒,这个序列驱动了人胎盘碱性磷酸酶(无膜锚定区域的SEAP,ClonTech)的分泌型表达,作为一种报告基因/增强子。p1435开创系的小鼠携带了60个串联的转基因拷贝。在乳腺中未检测到表达,但在肾、肌肉和肺中则有高水平的异位表达。(来源:J:82809)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
HsdWin:NMRI
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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