将Vcre基因,由CAG启动子驱动的构建,通过同源重组插入了Gt(ROSA)26Sor基因座中,这项操作在Wit 9 ES细胞中进行了。VCre/VloxP是一个源于Vibrio sp. p0908质粒的特定位点重组系统,VCre是一个识别并剪切自身特定靶位点(VloxP)的重组酶。(来源:J:263660)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6JJic
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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