Exon 3周围标记了loxP位点,接着是带有IRES-tandem-dimer红色荧光蛋白和polyA报告基因的构建,同时3'UTR插入了FRT引导的neo cassette,通过同源重组实现。随后,Flp介导的重组去除了neo cassette。(来源:J:265419)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Targeted
插入
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1
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7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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