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中文
靶向载体通过在编码小鼠NtsR1基因3'端末端序列的终止密码子和polyadenylation位点之间插入一个IRES-Cre，同时在IRES-Cre上游放置一个Frt-flanked NEO cassette来构建。通过同源重组正确重组的ES克隆被扩增后，注入到小鼠囊胚中以产生嵌合体雄性。这些小鼠随后与FlpO去失线杂交，以在一生中消除NEO cassette，从而实现Cre表达的持续性（来源：J:263745）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
