转基因构建包含一个200kb的人类BAC RP11-620F30,其中包含了完整的人类IL15(白细胞介素15)基因。小鼠能够表达出生理水平的人类IL15(7.1±0.3pg/ml,来源:J:101977)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
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1
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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