将一个Lox-STOP-Lox-hM3Dq-mCherry cassette插入到Advilin基因位点,替换掉Avil基因的第2外显子和66bp上游区域。这是一个由cre重组驱动的报告型突变,特定于感觉神经元的Avil基因在cre重组时会驱动mCherry表达。(来源:J:265202)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129P2/OlaHsd)F1
Targeted
插入,基因内删除
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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