使用包含Sox10调控区的BAC,将人类雌激素受体(ERT2)的突变配体结合域与Cre重组酶编码序列连接,并直接插入转录起始点下游。在BAC两侧的LoxP位点在微注射前被去除。Sox10调控区驱动CreERT2重组酶在神经管特异性表达。(来源:J:299312)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F2
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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